Définir la notion de méta-analyse, definition of meta-analysis

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A meta-analysis is a statistical method that combines the results of several randomized controlled trials verifying the efficacy and/or the cost/effectiveness ratio of a curative or preventive innovation on health and quality of life.

The researcher conducting this meta-analysis proceeds initially to be the most comprehensive inventory (also called systematic) of articles published in scientific and medical literature a question and referenced in large databases. For non-drug interventions, these include Pubmed, de ScienceDirect, de Embase et de PsycINFO. In a second step, the meta-analysis statistically re-uses data compiled for each study. This analysis focuses on a number of topics, giving weight to his conclusions.

Meta-analysis is used especially when clinical trial results seem contradictory. It can also detect methodological flaws and highlight a level of heterogeneity of the identified clinical trials. Blog in Health relies heavily on meta-analyzes for academic reviews.

The general message

A meta-analysis allows for the synthesis of studies on a specific issue. It gives an average value of the intensity of the effect of therapeutic intervention or a health care prevention health, quality of life and safety.

The message for health professionals

A meta-analysis is a comprehensive review of the scientific and medical literature. It is designed to answer a specific question. It gives an average value of the intensity of the effect of therapeutic intervention or a health care prevention based on data compiled from randomized controlled trial.

The message for researchers

The Consolidated Standards of Reporting Trials (CONSORT) aims to standardize the procedures for submission of randomized controlled trial in scientific journals and subsequently make it usable data in meta-analyzes. The CONSORT includes a list of items to be checked and a flowchart. Many leading medical journals and major publishing groups have adopted it. This presentation facilitates reading and a randomized controlled trial analysis.

A final form of meta-analysis is the Cochrane Reviews. This procedure analyzes the effectiveness of an intervention and its health risks compiled from randomized controlled trials systematically sorted data.


Cochrane Collaboration (2014). Website. Cochrane.

Consolidated Standards of Reporting Trials (2014). Website. CONSORT.

To reference this Blog en Sante © article.

Ninot G (2013). Definition of meta-analysis. Blog en Sante, L25.

© Copyright 2014 Gregory Ninot. All rights reserved.