Tag: essai randomisé contrôlé

 

Evidence of the Efficacy of Respiratory Rehabilitation

A study proved the efficacy of a 6-week multidisciplinary rehabilitation program for Chronic Obstructive Pulmonary Disease patients. A landmark randomized controlled trial by Griffiths and colleagues, published in The Lancet in 2000, tested the efficacy of a multidisciplinary program based on physical exercise, nutritional advice, smoking cessation and therapeutic education among 180 patients suffering from COPD. […]

Defining Meta-analysis

A meta-analysis is a statistical method that combines the results of several randomized controlled trials verifying the efficacy and/or the cost/effectiveness ratio of a curative or preventive innovation on health and quality of life. The researcher conducting this meta-analysis proceeds initially to be the most comprehensive inventory (also called systematic) of articles published in scientific and […]

Defining Cost-Efficacy

Budget cuts in health and rising expectations of improved quality of care impose arbitration on treatment and prevention priorities. These choices will be increasingly based on scientific, medical and economic hard evidence and not solely on the advice of clinicians on mechanistic studies, proof of concept or cohort analyzes. We have never been a greater […]

Defining Efficacy

The highest level of evidence of efficacy of therapeutic innovation or prevention is given by a randomized controlled trial. This experimental methodology provides the most rigorous demonstration of the effect of innovation on the endpoints measured at the beginning and end of the protocol. Are there profits on (biological psychological clinics, socio-professional and/or survival) health […]

Defining Control Group

Intervention research that supports the Blog in Health. The control group is the group of participants who will not test or therapeutic innovation in health prevention. People will take a placebo or follow the standard treatment (standard care). This choice will be based on a thorough analysis of the scientific and medical literature. The average […]

Defining Intervention Group

Intervention research that supports the Blog in Health. The group “intervention” of a randomized controlled trial is the group of participants who will test therapeutic innovation or prevention. This group is also known as “experimental.” The averages of the results before and after intervention effectiveness criteria measured are compared to those of the control group […]

Defining Outcome Measures

An endpoint, or its synonyms as interest factor and endpoint (English outcome), is a measurable indicator that the researcher assumes it will be modified by therapeutic innovation or action health prevention as part of a randomized controlled trial. There may be health indicators (clinical, biological, psychological, socio-professional and / or survival), quality of life (generic […]

Defining Randomized Controlled Trial

The randomized controlled trial is an experimental clinical research protocol that compared a group called “intervention” testing a new therapy or new share of health prevention and a group called “review” in the (usual care) standard recommendations or taking a placebo (placebo). The assignment of participants in one group is randomly (draw). This choice can […]

Defining Interventional Research

Intervention research or clinical research involving human subjects meets a precise specifications according to the principles of Evidence Based Medicine. It relies on a particular experimental protocol called randomized controlled trial or clinical trial phase 3 This experimental applied research aims to demonstrate the effectiveness of a treatment strategy or action health prevention with a […]

Defining Evidence Based Medicine

Blog in Health relies on a central concept, the concept of Evidence Based Medicine (EBM) or evidence-based medicine in French. This concept was developed by epidemiologists of McMaster University in Canada in 1980 (Sackett et al., 2000). It calls for all medical decision based on theoretical knowledge, judgment and experience but also on scientific evidence […]